Medical Director/ Senior Medical Director

S3 Science
10 Aug 2017
18 Aug 2017
Medical Director/Senior Medical Director We have new opportunities for two medical director/senior medical director roles to support our client's growing portfolio, one focussed on Immuno-oncology and one on Inflammation. Situated in the Cambridgeshire area. This is a permanent opportunity, offering a competitive salary as well as a full range of benefits. The Role A key figure in our medical team, reporting to the Chief Medical Officer, you will provide strategic medical guidance and lead the development of experimental immune-oncology and /or anti-inflammatory antibodies in the portfolio, beginning with the candidate selection phase of preclinical development and continuing through proof-of -concept (POC). Key Responsibilities Provide strategic medical guidance for the development of new antibodies that are in preclinical development Lead the early program teams, beginning at the time of Development Candidate (DC) nomination and approval to conduct toxicology studies Create the clinical development plan (CDP) that supports development beyond POC, combining medical knowledge with the expertise of other functions (eg clinical pharmacology, toxicology etc) Integrate preclinical information (pharmacology, toxicology, PK) and interpret its implications for clinical development, as articulated in the Investigator Brochure (IB) Collaborate with clinical scientists to develop, interpret and report clinical trial protocols Apply medical knowledge to guide the safe, ethical and efficient conduct of the trials under their responsibility, be knowledgeable of GCP guidelines and strive to maintain compliance with them Qualifications and Experience Degree of Medicine (MD) required PhD or board certification in a relevant therapeutic area is an advantage Expert level of knowledge in the main field of interest and/or assigned therapeutic area Significant industry/biotech experience of early-phase clinical trials or equivalent experience in the academic setting Thorough working knowledge of the application of PK/PD and biostatistics to clinical development and clinical trials Proven ability to analyse and interpret efficacy and safety data Knowledge of regulatory and GCP requirements Good business acumen within the CRO and drug development environment Excellent medical/scientific skills Exceptional communication, collaboration, influencing and leadership skills, with proven ability to lead a matrix team Excellent personal integrity, energy, drive and commitment to improving the clinical development at the client To Apply To apply for this role, simply apply to this advert, or alternatively you can send your most recent up to date CV Please note, only successful candidates will be contacted. All successful applications are subject to S3 Science's stringent vetting and security checks. S3 Science is proud to be an equal opportunities employer and is committed to creating a diverse environment. All qualified applicants will receive consideration for employment without regard to race, colour, religion, gender identity or expression, sexual orientation, national origin, genetics, disability, age or veteran status. This job was originally posted as